Where are we in the COVID-19 vaccine race?

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Large global trials of several COVID-19 vaccine candidates involving tens of thousands of participants are well underway with some having gathered sufficient data to seek emergency use authorization.

The following is what we know about the race to deliver vaccines to help end the coronavirus pandemic that has claimed more than 1.45 million lives worldwide:US drugmaker Pfizer Inc and German partner BioNTech SE released a full late-stage trial data analysis on Nov. 18 that showed their shot was 95% effective at stopping COVID-19, the highest efficacy rate so far.

Interim late-stage trial results for Russia's Sputnik V vaccine published on Nov. 11 showed the shot is 92% effective.The companies are testing their vaccines against a placebo - typically saline solution - in healthy volunteers to see if the rate of COVID-19 infection among those who got the vaccine is significantly lower than in those who received the dummy shot.

AstraZeneca said its interim analysis was based on 131 infections among participants who received the vaccine and those in a control group who were given an established meningitis shot. Russia's interim examination was conducted after 20 volunteers developed the disease.The World Health Organization ideally wants to see at least 70% efficacy in trials. The U.S.

AstraZeneca said on Nov. 23 it will immediately prepare the data to submit to regulatory authorities around the world that offer conditional or early approval.Yes, although China launched an emergency use program in July aimed at essential workers and others at high risk of infection that has vaccinated about one million people as of mid-November.

 

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