Pfizer says its vaccine is 90.7% effective against symptomatic COVID-19 in children ages 5 to 11

In a new document posted ahead of a key meeting of the US Food and Drug Administration's vaccine advisers, Pfizer says its vaccine is safe and 90.7% effective against symptomatic COVID-19 in children ages 5 to 11.

10/22/2021 8:00:00 PM

In a new document posted ahead of a key meeting of the US Food and Drug Administration's vaccine advisers, Pfizer says its vaccine is safe and 90.7% effective against symptomatic COVID-19 in children ages 5 to 11.

In a new document posted ahead of a key meeting of the US Food and Drug Administration's vaccine advisers, Pfizer says its vaccine is safe and 90.7% effective against symptomatic COVID-19 in children ages 5 to 11.

Pfizer/BioNTech are seeking FDA emergency use authorization of a two-dose regimen of their 10-microgram dose for children ages 5 to 11. The two doses would be administered three weeks apart.Last month, Pfizer released details of a Phase 2/3 trial that showed its COVID-19 vaccine was safe and generated a"robust" antibody response in children ages 5 to 11. The trial included 2,268 participants ages 5 to 11. Participants' immune responses were measured by looking at neutralizing antibody levels in their blood and comparing those levels to a control group of 16- to 25-year-olds who were given a two-dose regimen with the larger 30-microgram dose. Pfizer said the levels compared well with older people who received the larger dose, demonstrating a"strong immune response in this cohort of children one month after the second dose."

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The FDA's Vaccines and Related Biological Products Advisory Committee is scheduled to meet October 26 to discuss whether to recommend the vaccine for authorization for those ages 5 to 11.If authorized, this would be the first COVID-19 vaccine for younger children. The Pfizer/BioNTech vaccine is approved for people age 16 and older and has an EUA for people ages 12 to 15.

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