. It confirms earlier news reports that this single-dose adenovirus vaccine is efficacious, with an overall rate of 66%. This is not as high as the mRNA vaccines made by Pfizer and Moderna, which have efficacy rates around 95%, but it exceeds the 50% standard established by the WHO and is comparable to efficacy rates found with the AstraZeneca and Sinopharm vaccines.
Like the other vaccines made in Europe and the USA, the efficacy of the J&J vaccine decreases when it is tested against several of the new SARS-CoV-2 variants, including the variants that are in community transmission in South Africa and Brazil. Nonetheless, the vaccine was still able to protect immunized individuals from severe disease.
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