Newly discovered gene links stress, altered light-dark cycles to breast cancer

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A newly discovered gene, called Krüppel-like factor 9 (KLF9), showed a connection between a disrupted circadian cycle caused by stress and altered light-dark cycles and breast cancer.

A newly discovered gene, called Krüppel-like factor 9 , showed a connection between a disrupted circadian cycle caused by stress and altered light-dark cycles and breast cancer.This was according to research conducted by the University of the Philippines – Diliman College of Science.

“Normal body function involves a regular 24-hour pattern of biological activity, called the ‘circadian cycle,’ which is mainly controlled by the 12-hour light-dark cycle that, in turn, regulates several bodily functions such as sleeping and waking, digestion, and the action of various hormones at different times of the day,” said a NIMBB study.

With that, the NIMBB research team shed light on the importance of having a regular circadian cycle in their study entitled, “Circadian disruption is an emerging driver of breast cancer, with epidemiological studies linking shift work and chronic jet lag to increased breast cancer risk,” published on Feb. 23 in the journal, Cancer Cell International.

Source: Healthcare Press (healthcarepress.net)

 

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