Lower prostate cancer screening rates linked with more advanced cancers

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A decline in prostate cancer screening has been linked to subsequent increases in advanced cancers, according to data from the US Department of Veterans Affairs (VA), findings that may spur revisiting current US testing guidelines.

A new study, involving more than 5 million men over age 40 at 128 VA facilities across the country between 2005 and 2019, found that when screening was encouraged, later diagnoses of incurable advanced malignancies were less likely.

In 2018, based on new evidence, the panel modified its recommendation to limit prostate cancer screening to men ages 55 to 69, and then only if they "express a preference for screening after being informed of and understanding the benefits and risks." At individual facilities, higher rates of screening were linked with lower rates of subsequent diagnoses of advanced cancers. But for every 10% decrease in screening, there was a corresponding 10% increase in metastatic prostate cancer incidence five years later, the researchers said.

 

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