AstraZeneca antibody cocktail fails to prevent COVID-19 symptoms in large trial

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The study assesses whether the therapy AZD7442 could prevent adults who had been exposed to the virus in the past eight days from developing COVID-19 symptoms.

AstraZeneca said on Tuesday, June 15, a late-stage trial failed to provide evidence that its COVID-19 antibody therapy protected people who had contact with an infected person from the disease, a small setback in its efforts to find alternatives to vaccines.

The Phase III study, which has not been peer reviewed, included 1,121 participants in the United Kingdom and the United States. The vast majority, though not all, were free of the virus at the start of the trial. The company is banking on further studies to revive the product's fortunes. Five more trials are ongoing, testing the antibody cocktail as treatment or in prevention.

 

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