Scientists closer to first cancer vaccine | The Guardian Nigeria News - Nigeria and World News

•Moderna’s melanoma jab given ‘breakthrough’ drug status by US regulator, could be approved in months•Trendy intermittent fasting may raise risk of infections, heart disease, cancer, researchers suggestIn another study, experts say new blood test for prostate cancer could end ordeal of biopsies for thousands of men and that trendy intermittent fasting may raise risk of infections, heart disease and cancer.

The promising results prompted the United States Food and Drug Administration to issue the designation yesterday – which could slash the time it takes to be approved to up to eight months. If granted, priority review would mean the regulator would make a decision on approving the therapy within six months of Moderna submitting its application, rather than 10 months under standard review.

The vaccine is given to people post-surgery to prevent the tumor from returning, and it is tailored to each patient, meaning no two shots will be the same. Merck and Moderna said they plan to initiate a phase three study into the therapy this year, where it will be tested on potentially thousands of patients.

The new liquid biopsy works by picking up tumour cells from prostate cancer in the blood. A team including researchers from India and Imperial College London tried it on men with signs of suspected cancer, like an enlarged prostate or urinary symptoms. Researchers also said the study is among the first to show that skipping meals triggers a stress response in the brain that negatively affects immune cells. While some studies have claimed that intermittent fasting may be linked to longevity, recent research has suggested it may have the opposite effect.

Supporters suggest the diet prompts weight loss, lowers inflammation levels and can help people live longer. Scientists drew blood from mice at the start of the study, and at four, eight and 24 hours into the experiment. Samples were tested for monocytes — white blood cells made in the bone marrow that fight infections, heart disease and cancer.

Source: Healthcare Press (healthcarepress.net)

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