For about two weeks that Abiodun , a 22-year-old sickle cell carrier, spent on the hospital bed when he had another round of the ‘usual’ crisis, his father and a few family members around him struggled to keep hope alive, mumbling to themselves even as they watched him shuttle between life and death in excruciating pain.
Ogbonna et al in an article published in the Pan-African Medical Journal in February 2022 said about 50 million people live with sickle cell disorder globally and that Nigeria remained the epicentre, with between four and six million people. The researchers added that every year, not less than 300,000 children are born with the disease and Nigeria accounts for 100,000 to 150,000 newborns.
In addition to the enormous pain, they experience stunted growth, delayed puberty, swollen hands and feet, and frequent infections, among others. In its article titled, ‘Genetic scissors: a tool for rewriting the code of life’, the organisers of the prize said, “Researchers are already performing clinical trials to investigate whether they can use CRISPR/Cas9 to treat blood diseases such as sickle cell anaemia and beta thalassemia, as well as inherited eye diseases.”
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