‘High efficacy and cost-effective’ — WHO approves Oxford malaria vaccine for use in children

The World Health Organisation says it approved R21/Matrix-M, a malaria vaccine, developed by scientists at Oxford University, for the prevention of the disease in children.

The R21 vaccine is the second malaria vaccine recommended by WHO, the first being the RTS,S/AS01, which received a WHO “In areas with highly seasonal malaria transmission , the R21 vaccine was shown to reduce symptomatic cases of malaria by 75% during the 12 months following a 3-dose series,” the WHO said.“A fourth dose given a year after the third maintained efficacy. This high efficacy is similar to the efficacy demonstrated when RTS,S is given seasonally.

“At prices of US$ 2 – US$ 4 per dose, the cost-effectiveness of the R21 vaccine would be comparable with other recommended malaria interventions and other childhood vaccines.“The R21 vaccine was shown to be safe in clinical trials. As with other new vaccines, safety monitoring will continue.”

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