Bats are hosts to a range of viruses but don't get sick – why?

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Like all animal species, bats possess their own range of pathogens – viral, bacterial and fungal. Bats have therefore evolved with a set of viruses that...

to bind to cells as the current SARS-CoV-2. These viruses were similar enough to SARS-CoV that they were termed SARS-like coronaviruses. New viruses have been added to this group since then. So there is a significant diversity of coronaviruses circulating in bats, which may increase the probability that one of these viruses has the potential to become a zoonotic infection – in other words, can jump to humans.

In addition to traits that allow bats to tolerate a high body temperature, bats may also have other adaptations that mark their immune system as unusual or unique among mammals.that helps to control the antiviral response in bats during a viral infection. The mutation is in a gene called the stimulator of interferon genes , which is common to all mammals and has a crucial role in triggering the inflammation response during a viral infection.

 

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Like all animal species, bats possess their own range of pathogens – viral, bacterial and fungal.

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