Scientists discover how to transform white fat cells into calorie-burning beige cells, paving the way for weight-loss treatments.
A breakthrough may have been made in the fight against obesity after researchers discovered a method to transform white fat cells into beige fat cells, which are capable of burning calories.While humans can turn white fat cells into beige through diet or a cold environment, until now scientists believed the only way to mimic this natural process was by starting from stem cells.
However, since stem cells are scarce, Feldman set out to discover a method to directly transform white fat cells into beige ones with a simple switch.'For most of us, white fat is not rare and we're happy to part with some of it,' he said.In the study, he examined the role of a protein called KLF-15 in mice, which is known to influence metabolism and the function of fat cells.The research found that KLF-15 was much less abundant in white fat cells than in brown or beige ones.
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