The story of a vaccine: how Moderna’s big bet played out

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New book details how talent, leaps of faith and dogged determination brought the pharma company to world attention in 2020

The efficacy rates of the Moderna Covid-19 vaccine exceeded expectations at 94.5 per cent. Photograph: ShutterstockBefore Covid-19 few people had heard of Moderna. A 10-year-old pharmaceutical minnow that had no products on the market, it was on borrowed time with investors. Talent, leaps of faith and dogged determination brought it to world attention in 2020 in its successful bid to develop an mRNA vaccine that has subsequently saved millions of lives.

Speed and calculated risk-taking are a recurring theme in this book. Fauci believed it would take up to 18 months to create a safe vaccine, which would have been an impressive feat given that it normally takes 10 years. In the end, it was done in about half the time Fauci anticipated. That same month, however, researchers were able to report that the vaccine induced the production of antibodies which prevented the virus from infecting cells by blocking or interfering with the spike protein’s ability to attach itself inside cells. The potency was better than expected and Moderna knew it had cracked the code.

Drug companies issued a joint statement pledging to adhere to the highest ethical standards and scientific principles in bringing their vaccines forward, in a clear warning they were not going to let politics override public safety In September the drug companies took matters into their own hands, notwithstanding their intense rivalry in the race to produce the first vaccine. They issued a joint statement pledging to adhere to the highest ethical standards and scientific principles in bringing their vaccines forward, in a clear warning they were not going to let politics override public safety.

Source: News Formal (newsformal.com)

 

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IrishTimes I wonder how many lives it’s destroyed versus how many lives it’s saved?

IrishTimes Credit where credit is due tbf.

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