The fact that the vaccine prevented the virus from replicating in the nose is seen as particularly crucial in preventing it from being transmitted onward to others.
All vaccinated macaques produced high levels of neutralising antibodies that attack a part of the SARS-CoV-2 virus used to invade cells. — ABC News July 29, 2020 A major area of concern is that vaccines under development could actually backfire by amplifying rather than suppressing the disease. After two days, no replicating virus was detected in the lungs of seven of the eight macaques in both the low and high dose groups.None of the eight macaques in the high dose groups had detectable levels of virus in their noses two days after exposure.
The Moderna vaccine uses genetic material in the form of viral RNA to encode the information needed to grow the SARS-CoV-2 spike protein inside the human body to trigger an immune response.
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