Dear Dr. Roach: My mother-in-law died at age 73 from amyotrophic lateral sclerosis . There was no family history of the disease. My sister-in-law, age 72, is now experiencing occasional problems with lisping. Could this be the first sign of her developing familial ALS? She is in great physical condition otherwise, and she has no complaints of cramps or muscle weakness.
Ninety percent of people who develop ALS do not have a family history, but when there is a family history, the risk is much higher. When there is a family history, genetic testing can be helpful when combined with an evaluation by a neurologist. I’d recommend that your sister finds a neurologist specifically trained in neuromuscular diseases.
Recently, my bowel movements have changed, becoming less frequent and more difficult. I am worried that I should have gotten the colonoscopy and that perhaps colon cancer is developing. I don’t have blood in my stool and have taken the fecal occult blood test with negative results.
Source: Healthcare Press (healthcarepress.net)
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