Researchers 'revive' organs in dead pigs, raising questions about life and death

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Scientists have rebooted vital organs of dead pigs in an experiment bioethicists say may force a rethink of how the body dies, and that further blurs the boundaries between life and death.

The experiments also bolster findings from another Yale-led project three years ago that involved disembodied pigs’ brains. Using a similar perfusion system called BrainEx, researchers restored some functions in brains taken from pigs four hours after they were killed in a meatpacking plant.Article content

Donor organs can be retrieved from people who are declared brain-stem dead. They’re medically and legally dead, but their hearts are still beating. But seat belt and helmet laws and advances in treating brain injuries means fewer people are dying from brain death. In both the BrainEx and OrganEx experiments, the researchers, who did continuous EEG monitoring of the animals’ brains, found cellular activity in some areas of the brain had been restored. At no point did they see the kind of electrical activity that would indicate consciousness or awareness, they said.

“The next step is that we’re hoping to see complete tissue and organ recovery and, of course, eventually, to transplant these organs,” he said. He’s also pro-transplant — “I’m not anti-transplant in any way, shape or form.” However, “what hits me like a tonne of bricks is that you are really manipulating the boundary between life and death.”

 

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