. Untreated, depression can decrease quality of life and exacerbate other symptoms, including fatigue, pain and cognitive changes.
Patients with both MS and depression were found to have a mortality rate from any cause of 10.3 cases per 100,000 person-years . The mortality rate for people with MS but no depression was 10.6; for people with depression but not MS, it was 3.6; and for those with neither, it was 2.5.
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