Canadian Blood Services warns of imminent shortage of take-home immune globulin drug

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It is one of the most widely used medications made from human plasma.

FRED THORNHILL

CBS, the national blood authority which is responsible for buying and distributing plasma-derived drugs outside Quebec, issued its first “amber phase advisory” for immune globulin to hospitals across the country last week, prompting a working group of immunologists, neurologists and patient advocates to recommend that, for now, no new patients be started on the self-administered form of the drug.

In the meantime, Canadian Blood Services , which opposes compensating Canadian donors, is looking at collecting more plasma from unpaid volunteers in hopes of reducing the country’s reliance on paid Americans to meet its demand for IG. Isra Levy, CBS’s vice-president of medical affairs and innovation, stressed that there is only a potential, not an actual, shortage of subcutaneous immune globulin, or SCIg, which patients usually infuse under the skin in their abdomen or thighs.

“We’ve really been struggling to tease out what, in fact, is going on with these numbers,” Dr. Levy of CBS said. “What no one forecast … is the degree to which there would be an increase in the preference of clinicians and patients for the subcutaneous product.”Christina Hickey, a 39-year-old mother of three living near Peterborough, Ont., is one of the approximately 400 patients who have started infusing IG at home since the fall.

Still, the looming shortage of SCIg is “really scary,” according to Whitney Goulstone, the executive director of the Canadian Immunodeficiencies Patient Organization

 

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