Evidence is mixed or lacking, but experts say it makes sense to treat hypertension to lower dementia risk, particularly in middle age.
. Long-standing evidence shows that treating hypertension can reduce its vascular consequences, but whether that is true for neurodegeneration is less clear.."There is no question in the literature that untreated high blood pressure may lead to dementia," he said."The open question is whether treating blood pressure is sufficient to decrease or stop the progress of dementia.
"It is well known that hypertension affects the vasculature, and the vasculature of the brain is not spared," agreed Eileen Handberg, PhD, ARNP, a member of the Hypertension Workgroup at the American College of Cardiology and a professor of medicine and director of the Cardiovascular Clinical Trials Program in the University of Florida, Gainesville, Florida.
"The relative contributions of time in range versus treating to a target for blood pressure require further study," said Elkind."It is likely that the cumulative effect of blood pressure over time has a big role to play — and it does seem clear that midlife blood pressure is even more important than blood pressure late in life."
"Treating high blood pressure in older adults could affect the course of further progressive cognitive decline by improving vascular health and preventing strokes, which likely exacerbate nonvascular dementia," Elkind suggested."Most people with dementia have a combination of vascular and nonvascular dementia, so treating reversible causes wherever possible makes a difference."
Blood Dementia Stroke Cerebrovascular Accident CVA - Cerebrovascular Accident Blood Vessels Myocardial Infarction CV Risk Cardiovascular Risk CV Risk Factors Cardiovascular Risk Factors Cardiovascular Risk Management Brain Cognitive Impairment Mild Cognitive Impairment MCI - Mild Cognitive Impairment Minimal Cognitive Impairment MCI Mild Cognitive Impairment (MCI)
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