Although rates of colorectal cancer are on the decline, the incidence among younger people continues to rise.
In their perspective, Giannakis and Ng highlight several patterns that have emerged among individuals with early-onset CRC.
This idea is supported by the fact that survival rates among younger patients with metastatic early-onset CRC are similar to those among older patients, despite the fact that younger patients are often healthier overall, they undergo more intensive therapy, and they experience fewer side effects from treatment.The evidence to date suggests that factors that predispose to cancer are more prevalent among younger patients. The most common such factor is Lynch syndrome.
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