A major research initiative has catalogued thousands of types of brain cells and where they are located, producing a resource that should help study neurological diseases in fine detail
Researchers have drawn up the most detailed description ever created of the human brain, based on the thousands of different cell types that make it up.
It is designed to lay the groundwork for further research into conditions that affect the brain, including neurological conditions such as Alzheimer’s and Parkinson’s disease, as well as mental health problems such as depression and schizophrenia. “If you’re going to explore a new country, you need a map so you know where you’re going,” saysGet the most essential health and fitness news in your inbox every Saturday.
But it was difficult to precisely identify the multitude of different neurons that exist until the advent of a technique calledThis analyses the genetic material of a single cell to see which genes are turned on or off – in other words, which proteins it is making. The first draft involved efforts by multiple international research teams, sequencing millions of brain cells altogether.Linnarsson was involved in several of the projects, including carrying out single-cell sequencing of 105 anatomical locations from four adult brains. The project identified 3313 different types of brain cells.
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