Andrew Vaughn's tiebreaking, two-run double in the ninth inning lifted the White Sox to victory over the Astros in their season opener.
Reynaldo Lopez allowed a soaring solo home run to the second deck in right field to Yordan Alvarez with one out in the ninth but finished for the save.
He was replaced by Aaron Bummer, who walked Kyle Tucker to load the bases. A wild pitch with two outs allowed Alvarez to score, putting Houston up 1-0. Framber Valdez allowed six hits and struck out four in five scoreless innings in his second straight opening-day start for Houston.
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