Dr. William A. Haseltine is a distinguished scientist, philanthropist, author, and entrepreneur renowned for his pioneering work in genomics and regenerative medicine. A former Harvard Medical School professor, he has made many significant contributions to cancer and HIV/AIDS research.
Recent breakthroughs in genetics research may have uncovered new genes underlying common psychiatric disorder s. Schizophrenia and bipolar disorder affect more than 64 million people around the world. These disorders are strongly influenced by genetics. No one gene, however, determines one’s risk of developing schizophrenia or bipolar disorder . Rather, it is likely that a host of genes contribute to risk.
Our genes are a combination of the DNA we inherit from our parents. We have two copies of each gene, one from mom and the other from dad. These randomly assorted gene pairs determine traits like hair texture, eye color, and even some health risks. Some traits are dominant, meaning that only one copy of the variant is needed for expression. Others are recessive and only show up if both copies are the same. This is referred to as Mendelian inheritance, named after Dr.
Alexander Urban, senior author of this study and Associate Professor at Stanford, describes, “Looking for only simple variations is like proofreading a book manuscript and searching exclusively for typos that change single letters. You are overlooking words that are scrambled or duplicated, or in the wrong order—you might even miss that half a chapter is gone.” Certain disorders, in fact, may be linked to long, complex spelling changes in an individual’s genes.
Schizophrenia Whole Genome Psychiatric Disorder Artificial Intelligence
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