These Stick-On Biosensors Unlock Sweat Science for Athletes

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These Stick-On Biosensors Unlock Sweat Science for Athletes
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WIRED Can accurately analyze sweat to provide real-time hydration guidelines. Non-invasive patch to adhere to your arm. TIRED Nix has so far provided thin data on how its new platform has been scientifically validated. Connectivity kinks. 📷: Nix

Since that test, Nix has added compatibility with Garmin devices, one of which I do have, which should have made it easier to check the data on the fly. I was able to download the Nix widget easily enough to my Garmin Edge 1030 Plus GPS device and pair it with Nix. But the Nix data field on my Garmin had only two measurements: fluid loss and electrolyte loss, which would require some mathematical skills in the field to determine how much and what I would need to drink in order to replenish them.

To work with the Garmin watch, however, Nix still needs a Bluetooth connection to the iPhone. I paired the sensor to my phone before I left the house, but by the time I reached the trailhead, the Bluetooth connection was lost. I tried again the next day and was successful at first. After I spent 30 minutes happily sweating on the trail, I checked the Nix app and got the message “Check Bluetooth connection.

Curious to hear what a scientist might say about Nix, I emailed Noé Brasier from ETH Zurich and University Hospital Basel in Switzerland, who had chaired an interdisciplinary session on biosensors during a virtual congress called. Brasier, whose focus is clinical applications of sweat analysis, told me, “I am convinced that noninvasive molecular diagnostics will help physicians to extend and improve remote patient-monitoring in the future.

Upon examining Nix’s methodology, he noted that “extrapolating the local sweat rate to the whole body sweat loss is challenging, as we sweat differently along the body surface.” He explained that, among other issues, there are different local sweat rates and different sweat gland types throughout the body.

In response to Brasier’s concerns about scientific validation, Nix confirmed that there have so far been no external reviews of its in-house validation studies. Now that the product is launched, it says that’s where it will focus. “This product will be the core of Nix for a little bit to come,” says Cass, the founder. But she has bigger goals, not a bad gamble, considering the market for biosensing skin patches is expected to reach $18 billion by 2027.

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