This article discusses the urgent crisis of antibiotic resistance, highlighting its impact on global health, the lack of new antibiotics in development, and the role of public behavior in exacerbating the problem.
went largely unnoticed—perhaps because it was published in Italian—until American researchers rediscovered the compound and recognized its potential to prevent transplant rejection. Meanwhile, Alexander Fleming’s 1928 discovery of penicillin changed the course of medicine and saved countless lives by ushering in the antibiotic era. Yet despite these breakthroughs, we now face a crisis: the misuse and overuse of antibiotics has led to a rise in multidrug-resistant bacteria.
This poses serious challenges not only for everyday medical treatments but also for surgeries and cancer chemotherapy.a critical lack of new antibiotics in development to combat antimicrobial resistance. Their report showed few potential treatments for infections already resistant to available drugs. Dr. Mario Raviglione, Director of the WHO Global Tuberculosis Program in 2017, highlighted a particularly alarming statistic: in over 70 years, only two new antibiotics for treating multidrug-resistant tuberculosis have reached the market., more than one million deaths were directly caused by antibiotic resistance in 2019, with nearly five million deaths associated overall with antimicrobial-resistant infections. The World Bank also warns that these challenges will lead to additional healthcare costs reaching 1 trillion USD by 2050. A major reason for this crisis is public behavior. One in three individuals has used leftover antibiotics or obtained them without a prescription, undermining proper treatment and fueling resistance. Antibiotics are often taken for the wrong reasons—such as viral infections—and such misuse makes it difficult for health authorities to monitor and control their overuse. Collectively, this undercuts efforts to keep antibiotics effective for serious bacterial infections.Ada Yonath became the first woman from the Middle East to win a Nobel Prize in science in 2009, sharing the Nobel Prize in Chemistry with Venkatraman Ramakrishnan and Thomas A. Steit
ANTIBIOTIC RESISTANCE PUBLIC HEALTH GLOBAL HEALTH MEDICINES MICROBIOLOGY
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