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If the idea of driving down a winding road makes you feel queasy, spare a thought for the mice employed in a new study, which sought to pinpoint the brain cells responsible for motion sickness.
The animals' body temperature dropped, and they shunned food and cowered in their cages – all clear signs that they were experiencing something akin to the motion sickness humans do. Cold sweats, anyone? To figure out which cells fired in response to motion sickness, Machuca-Márqueza and colleagues inhibited different subsets of neurons within the vestibular nuclei and then strapped the mice back on the spinner to see if those changes alleviated motion sickness.
Switching on those same neurons triggered motion sickness-like behaviors in mice without spinning. Talk about sensory mismatch; that would be a real trip.
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