Synapse-tuned CARs enhance immune cell anti-tumor activity
We would like to acknowledge the technical support from H. Houke, C. O’Reilly and A. Chabot. This work was supported by the St. Jude Sumara Fellowship , the American Lebanese Syrian Associated Charites , the ChadTough Defeat DIPG Foundation , National Institute of Neurological Disorders and Stroke grant R01NS121249 , the Rally Foundation for Childhood Cancer Research , the Garwood Postdoctoral Fellowship and National Institutes of Health /National Cancer Institute grant P30 CA021765.
Animal imaging was performed by the Center for In Vivo Imaging and Therapeutics, which is supported, in part, by NIH grants P01CA096832 and R50CA211481. Cellular images were acquired at the St. Jude Childrenʼs Research Hospital Cell & Tissue Imaging Center, which is supported by St. Jude and NCI P30 CA021765. Gene editing of cell lines was performed by the Center for Advanced Genome Engineering , which is supported, in part, by NCI P30 CA021765.
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