Study Uncovers Hidden Link Between REM Sleep Apnea and Memory Decline in Alzheimer’s

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Study Uncovers Hidden Link Between REM Sleep Apnea and Memory Decline in Alzheimer’s
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A study led by UC Irvine links the frequency of sleep apnea events during REM sleep to severe verbal memory impairment in older adults at risk for Alzheimer’s. The research emphasizes the need for specific clinical focus on REM-related apnea events to improve diagnosis and treatment, especially noting differences in sleep apnea patterns between men and women.

“Our findings identified the specific features of sleep apnea that are associated with memory, which is important because clinically, events occurring during REM sleep are often overlooked or minimized,” said co-corresponding author Bryce Mander, UC Irvine associate professor of psychiatry & human behavior. “Most hours of sleep are non-REM, so the overall averages of apnea severity can look much lower than what is typically observed during REM sleep.

“Our findings highlight the intricate relationship among sleep apnea, memory function, and Alzheimer’s risk,” Mander said. “Identifying and addressing REM-specific events are crucial for developing proactive, personalized approaches to assessment and treatment that are tailored to individual sleep patterns.”

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