Scientists introduced alligator DNA into catfish to create hybrid

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Scientists introduced alligator DNA into catfish to create hybrid
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The disease-resistant catfish could one day be used for human consumption.

A team of scientists inserted an alligator gene into the genomes of catfish. The alligator gene called cathelicidin is an antimicrobial gene that plays a role in the animal's innate immune response, providing defense against various pathogens, including bacteria and viruses.

Researchers inserted the gene into the part of the catfish genome that codes for an essential reproductive hormone. The produced hybrids showed increased disease resistance and sterility.not just contributes to climate change but also suffers from its impacts.

Catfish are not just highly susceptible to bacterial infections and abiotic stresses but have also developed antibiotic resistance. Scientists are trying to give these freshwater farm fish an edge against the circumstances by infusing them with a disease-fighting gene from alligators. system has revolutionized gene modification, making gene editing more precise, efficient, and accessible.

The cathelicidin transgenic fish's survival rate is 100-400 percent more than their native counterparts. The sterility of these hybrids helps preclude their impact on ecosystems and "prevent the establishment of transgenic or domestic genotypes in the natural environment," says the team.

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