Researchers achieve a significant advancement in early diagnosis of bipolar disorder in adolescents

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Researchers achieve a significant advancement in early diagnosis of bipolar disorder in adolescents
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Researchers report significant strides in enhancing early diagnosis of bipolar disorder in adolescents. They demonstrate the efficacy of integrating multimodal MRI with behavioral assessments for greater diagnostic precision.

Bipolar disorder is a severe neuropsychiatric condition that often emerges during adolescence and is characterized by extreme mood swings., published by Elsevier, researchers report significant strides in enhancing early diagnosis of bipolar disorder in adolescents. They demonstrate the efficacy of integrating multimodal MRI with behavioral assessments for greater diagnostic precision.

The team used advanced brain imaging techniques to study adolescents who are at risk for bipolar disorder. A group of 309 subjects, including bipolar disorder patients, offspring of bipolar disorder patients , non-bipolar disorder offspring with subthreshold symptoms, and healthy controls, was analyzed. Behavioral attributes were integrated with multimodal MRI features.

Commenting on the significance of the study, John Krystal, MD, Editor of Biological Psychiatry, says,"We have long expected that brain imaging would help to improve the psychiatric diagnostic process. Here we have a very promising example where the information gained from several forms of MRI, combined with clinical information, improve upon the accuracy of traditional clinical diagnosis.

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