A preliminary study says the psychedelic chemical in “magic mushrooms” may ease depression in some hard-to-treat patients.
FILE - In this May 24, 2019, file photo a vendor bags psilocybin mushrooms at a pop-up cannabis market in Los Angeles. Despite pandemic conditions that made normal signature-gathering almost impossible, activists in the nation's capital say they have enough signatures for a November ballot initiative that would decriminalize natural psychedelics such as mescaline and psilocybin mushrooms.
Commenting in a journal editorial, Madras said the study is the most rigorous study to date evaluating psilocybin for treating depression. She was not involved in the research. Depression symptoms declined in all three groups, with the greatest initial improvement in the highest-dose group. At three weeks, 37% of high-dose recipients had substantially improved. But those effects weren’t as good as seen in studies of standard antidepressant drugs, and the results waned in the following weeks.Compass Pathways, a London-based firm developing psilocybin for commercial use, paid for and helped conduct the study.
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