Pittsburgh Pirates vs. Arizona Diamondbacks betting odds, how to watch, probable pitchers, and MLB picks and props for Wednesday, May 6.
Paul Skenes and the Pittsburgh Pirates look to get back on track when they take on the Arizona Diamondbacks on Wednesday night. The Snakes shut out the Pirates 9-0 in the series opener on Tuesday night, and Skenes is coming off a shaky outing himself.
Pittsburgh is still 19-17 on the season and 8-8 on the road, while Arizona is back up at 17-17 overall and 10-6 at home. Here are the odds, probable pitchers, and predictions for Pirates vs. Diamondbacks on Wednesday, May 6. After posting an ERA under 2.00 in each of his first two seasons, Skenes’ ERA has ballooned all the way up to 2.91 through seven starts this year.
He allowed five runs on seven hits with nine strikeouts and no walks in his last start against the Reds. The youngster made two starts against the Diamondbacks last season, allowing no runs on seven hits with one walk and 16 strikeouts in 12.2 innings. Michael Soroka is looking to bounce back from a really rough outing. The Brewers tagged him for eight runs on 10 hits in just three innings on April 30.
That came after Soroka had a few solid outings against the White Sox, Blue Jays, and Phillies. The veteran hasn’t pitched against the Pirates since 2019 when he was with Atlanta. Skenes went OVER 6.5 strikeouts in both starts against the Diamondbacks last season, and has done so in each of his last two starts as well. The right-hander is starting to get that strikeout stuff back, which is bad news for the Diamondbacks and rest of the league.
You can play it safe and take OVER 5.5 if you so choose, as he topped out at six strikeouts in two earlier starts this season, but I’ll take these plus odds for Skenes to get up to at least seven against the Snakes. The Pirates swept the Reds prior to getting shut out last night in Arizona. They now have Skenes on the mound against a washed up Soroka, and the line is only -126?
It’s not as if the Diamondbacks have been hot themselves. They lost four straight prior to last night’s win, scoring 10 runs in that span. If you or someone you know has a gambling problem and wants help, call 1-800-GAMBLER. Ryan is a sports betting writer at Sports Illustrated.
He has experience working for NHL.com, NBC Sports, Covers, and more throughout his decade in the industry. As a Philadelphia native, he understands the passion and pain that come with being a sports fan.
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
‘May the fourth be with you:' How the 4th day in May became a galactic holidayMay 4 is 'Star Wars' Day. Here’s how to reply to “May the fourth be with you” — and how to join the galaxy's biggest celebration.
Read more »
Former Diamondbacks Reliever Released by BravesOne of the D-backs' former relievers moves on.
Read more »
Pirates vs Diamondbacks Preview: Odds, Pitchers, and PredictionsA preview of the upcoming baseball game between the Pittsburgh Pirates and the Arizona Diamondbacks, including analysis of pitcher performances, team form, and betting odds. The Pirates are on a hot streak while the Diamondbacks are struggling.
Read more »
The 2 Prospects That Stood Out to the Diamondbacks the Most in AprilThese two players were named the D-backs' MiLB player and pitcher of the month.
Read more »
2 Diamondbacks Players Outrighted to Minor LeaguesThe D-backs make a roster move.
Read more »
The Diamondbacks' Best Story Just Keeps Getting BetterThe Diamondbacks' most heartwarming success story of 2026 doesn't seem to end.
Read more »