Nobel win for Swede who unlocked secrets of Neanderthal DNA

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Nobel win for Swede who unlocked secrets of Neanderthal DNA
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He spearheaded the development of new techniques that allowed researchers to compare the genome of modern humans and that of other hominins.

People outside Africa have 1-2% of Neanderthal genes. Neanderthals were never in Africa, so there’s no known direct contribution to people in sub-Saharan Africa.

“By mixing with them after migrating out of Africa, Homo sapiens picked up sequences that improved their chances to survive in their new environments,” Wedell said. For example, Paabo said he was surprised to learn of his win, and at first thought it was an elaborate prank by colleagues or a call about his summer home in Sweden.

Paabo’s father, Sune Bergstrom, won the Nobel prize in medicine in 1982, the eighth time the son or daughter of a laureate also won a Nobel Prize. In his book “Neanderthal Man: In Search of Lost Genomes,” Paabo described himself as Bergstrom’s “secret extramarital son” — something he also mentioned briefly on Monday.“The biggest influence in my life was for sure my mother, with whom I grew up,” he said in the Nobel interview.

The Human Genome project, which ran from 1990-2003, “got us the first sequence of the human genome, and we’ve improved that sequence ever since,” Green said. “We should always be proud of the fact that we sequenced our genome. But the idea that we can go back in time and sequence the genome that doesn’t live anymore and something that’s a direct relative of humans is truly remarkable,” Green said.

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