Science, Space and Technology News 2024
Research from the University of Arizona Health Sciences shows that Cannabis sativa terpenes are as effective as morphine in treating chronic pain and have fewer side effects. Combined with morphine, they offer enhanced pain relief, presenting a promising alternative to opioids with lower addiction risks. Future studies will focus on potential combination therapies to optimize pain management.
John Streicher, PhD, is a member of the University of Arizona Health Sciences Comprehensive Center for Pain & Addiction and a professor of pharmacology at the College of Medicine – Tucson. Credit: Noelle Haro-Gomez, University of Arizona Health Sciencesis unique in that it contains up to 150 terpenes with multiple terpenes acting as the dominant species.
“That was really striking to us, but just because something relieves pain doesn’t necessarily mean it’s going to be a good therapy,” Streicher said.Opioids are often used to treat many types of pain, but they can come with a host of unwanted side effects. Opioids activate the brain’s reward system, which is what can lead to addiction, and can cause tolerance, a condition that occurs when the body gets used to a medication and needs increasingly larger doses to have the same effect.
Finally, researchers tested different routes of terpene administration: injection, oral dosing, and inhalation of vaporized pure terpenes. They found that when terpenes were given orally or inhaled, the effects were significantly reduced or absent.
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