Multimodal single-cell and whole-genome sequencing of small, frozen clinical specimens - Nature Genetics

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Multimodal single-cell and whole-genome sequencing of small, frozen clinical specimens - Nature Genetics
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Multimodal sequencing achieves high-quality results from small volumes of frozen tumor specimens CUSEAS NatureGenet

We thank H. Hibshoosh at Columbia University for fruitful discussions. We thank the members of the CUIMC Human Immune Monitoring Core for technical advice. Y.W. is supported by National Institutes of Health , National Institute of Allergy and Infectious Disease training grant . B.I. is supported by the NIH, National Cancer Institute , a Burroughs Wellcome Fund Career Award for Medical Scientists, a Velocity Fellows Award, the Louis V. Gerstner, Jr.

Yiping Wang, Johannes C. Melms, Amit Dipak Amin, Patricia Ho, Somnath Tagore, Jana Biermann, Lindsay Caprio, Shaheer A. Khan, Brian S. Henick, Gary K. Schwartz, Richard D. Carvajal & Benjamin Izar Department of Systems Biology, Program for Mathematical Genomics, Columbia University, New York, NY, USADepartment of Biomedical Engineering, Columbia University, New York, NY, USAColumbia Center for Translational Immunology, Columbia University Irving Medical Center, New York, NY, USAVagelos College of Physicians and Surgeons, Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY,...

Yohanna Georgis, Shaheer A. Khan, Brian S. Henick, Alison M. Taylor, Gary K. Schwartz, Richard D. Carvajal, Elham Azizi & Benjamin IzarIrving Barrera, Matan Hofree, Evan Z. Macosko & Fei ChenSomnath Tagore & Benjamin Izar Department of Medicine, Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA, USAParker Institute for Cancer Immunotherapy, San Francisco, CA, USAEvan Z. MacoskoDepartment of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USAElham Azizi

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