Researchers have designed a device that can help test treatments in patients with gliomas, a type of tumor that originates in the brain or spinal cord.
The shape and size of a grain of rice, the new device can conduct dozens of experiments at once to study the effects of new treatments on some of the hardest-to-treat brain cancers.
One challenge in developing targeted therapies for glioma is that it can be difficult to test many different combinations of drugs in tumor cells, because it's only possible to treat patients with one approach at a time. This has been a significant barrier for hard-to-treat cancers like gliomas, for which combination therapies are a promising avenue.
In the time the device is implanted -- about 2-3 hours -- it administers tiny doses of up to 20 drugs into extremely small areas of the patient's brain tumor. The device is removed during the surgery and the surrounding tissue is returned to the lab for analysis.
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