Lauder family pledges $200M to its Alzheimer’s research work

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Lauder family pledges $200M to its Alzheimer’s research work
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Lauder family pledges $200M to its Alzheimer’s research work -

NEW YORK — The sons of cosmetics giant Estée Lauder, along with her four grandchildren, pledged $200 million Tuesday to the Alzheimer’s Drug Discovery Foundation, a nonprofit the family founded to support research into finding a cure for the disease.

Starting with a $100 million gift from their mother, the Lauder sons chose to invest in early research of potential treatments using what they called “venture philanthropy,” meaning any returns on their investments were put toward future research. The family also pledges to cover the organization’s expenses so all outside donations go entirely to funding research, Roithmayr said.

The FDA has approved two drugs that target the buildup of amyloid, though the 2021 approval of Biogen’s Aduhelm garnered controversy after the agency overruled its own independent scientific advisers. Legembi, a second drug, approved in January, is the first that’s been convincingly shown to slow the decline in memory and thinking that defines Alzheimer’s by targeting the disease’s underlying biology.

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