Patients receiving kidneys transplanted from donors with either resolved or active COVID-19 show no greater risk of poor outcomes or death, shows new research.
"Despite…having zero cases of COVID-19 transmission through kidney transplantation, kidney transplant providers continue to discard these highly valuable organs," Alhamad, of the Division of Nephrology, Washington University, St. Louis, Missouri, told"Our study shows no increased risk of rejection and no increased risk of kidney failure with the use of kidneys from COVID-19–positive donors," Alhamad emphasized.
However, an analysis of kidney utilization stratified by year shows the lower rates of use largely concentrated early on: in 2020, the nonuse of kidneys from donors with active COVID-19 donors was as much as 11 times higher compared with kidneys from donors without COVID-19 , but the rate of nonuse from active COVID-19 donors declined significantly by 2021 , and dropped further by 2022 .
Furthermore,"Transplant of kidneys from donors with resolved or active COVID-19 was not associated with increased risk of all-cause graft loss, all-cause death, acute rejection, delayed graft function, or longer hospitalization over more than 2 years of follow-up compared with kidneys from COVID-19–negative donors," the authors write.
Previous studies that stoked concerns about use of organs from patients with COVID-19 included a recentshowing persistent SARS-CoV-2 organ and brain infection in patients who had received a COVID-19 diagnosis as early as 230 days before their death.
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