In the wake of Chantix's recall, Varenicline use for nicotine dependence dropped by 75% Nicotine Chantix Varenicline NicotineDependence JAMANetworkOpen VCU McDonaldAHC
By Dr. Priyom Bose, Ph.D.Feb 7 2023Reviewed by Aimee Molineux Tobacco is associated with immediate and long-term adverse clinical outcomes, including morbidity and mortality. Although Pfizer’s Chantix showed prominent efficacy for dry eye disease treatment, its main utility has been in promoting smoking cessation. Put simply, varenicline is used for tobacco dependency treatment.
The US Food and Drug Administration allowed the distribution and use of the Canadian generic Apo-varenicline soon after the initial recall of Chantix. Later, the first FDA-approved generic varenicline became available. Study Findings Among 21,653,835 and 19,978,911 patients, 312,708 prescriptions for varenicline were filled by 238,258 patients. After Chantix production was halted, a significant reduction in the prescribed varenicline was observed. This finding implies that a significant decrease in the use of varenicline occurred after the removal of Chantix from the market. Subsequently, no significant change in the use of sustained-release bupropion or NRT was observed throughout the study period.
Study Insights The authors pointed out that in the US, the reduction in varenicline use was not due to a dearth in availability but due to accessibility. Two of the factors associated with the reduction in varenicline use are a lack of awareness among clinicians and patients regarding the availability of varenicline and concerns about nitrosamine.
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Murder probe after man found dead at Heywood houseThe death of grandad Geoffrey Ives, 75, in January is being treated as suspicious by police.
Read more »
F1 rumours: Ferrari shave off two to three kilograms with F1 2023 challengerIt has been reported that the 2023 Ferrari challenger will come out of the blocks two to three kilograms lighter than the F1-75.
Read more »
13,000 illegal vapes confiscated in Glasgow shop crackdownThe vapes were seized for reasons including tank capacity and nicotine strength exceeding permitted levels, with council officials also expressing worry that colourful, sweet-flavoured vapes appeal to youngsters
Read more »
NI vape company removes Elf Bar products over nicotine strength concerns'We are disappointed with news today with regards to compliance issues with other vape providers in the industry'
Read more »