Allergenimmunotherapy is the only treatment that targets the underlying pathophysiology of allergy with disease-modifying effects. MedTwitter
"Real-world data for AIT complement those from randomized controlled trials.
The researchers summarized and evaluated data on long-term effectiveness of allergen immunotherapy shots, tablets and drops for four endpoints: allergic rhinitis,For allergic rhinitis progression, they compared the number of prescriptions for symptomatic treatment of allergic rhinitis with or withoutduring follow-up vs pre-index compared to a non-AIT group receiving only symptomatic treatment.
Asthma development and progression were hampered for most endpoints in patients treated with most preparations, compared with the non-AIT group receiving only anti-asthma medication.In adherence to AIT medication, although AIT decreased during the recommended 3-year treatment period, most studies showed higher adherence to subcutaneous than to sublingual AIT.
"Including randomized controlled clinical trials is a strength of the study, but using prescription medication to track symptoms is a weakness," noted Lugar, who was not associated with this research.
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