Science, Space and Technology News 2024
Research on antimicrobial-resistant E. coli in dogs has identified genetic mutations that help the bacteria trap antibiotics, indicating potential new treatment strategies and emphasizing the importance of dogs in understanding human infections.
The research identifies obsolete genes in E. coli that trap antibiotics, offering new avenues for therapy and enhancing antibiotic stewardship in veterinary practices. “I like to think of it as a serendipitous event of evolution, because it appears that these capsule proteins have been repurposed to trap antibiotics,” said Laura Goodman, assistant professor at Cornell University and the paper’s senior author.
Dogs tend to share similar E. coli strains as their owners and are treated with similar antibiotics. Two particular classes of antibiotics – third generation cephalosporins and quinolones – are considered critically important by the World Health Organization.
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