‘It takes people who look at the weird things and say, “Why is that?” ‘
Researchers at the University of California, Irvine have discovered a fascinating connection between bothersome hair-sprouting skin moles and a potential breakthrough in the cure for baldness. June 26, 2023 at 3:50 a.m.
“Instead of studying only mouse fur — research in this area is usually done with mouse fur — we said, ‘Enough of that. Let’s look at human hair. The solution to human hair loss is in humans.’” Over some 10 years of work, the researchers identified a chemical released by a mole’s pigmented cells that “potently stimulates hair follicle stem cells for robust hair growth.” That molecule is osteopontin.
Now, senescent cells are often viewed as, you know, sort of useless — detrimental to regeneration, driving the aging process. But this research shows the old dog can do some cool tricks.there taking up space. They “linger around and secrete a bunch of stuff,” as Plikus put it. “They use molecular language — you can’t shut them up. They keep talking talking talking, communicating with non-aged cells, including stem cells.
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