People with MS who have a particular genetic variant required assistance walking more than 3 years earlier than those without it
study using data from 22,389 people with multiple sclerosis. These types of studies use statistical analysis to pinpoint genes associated with certain characteristics, such as multiple sclerosis severity.
After analysing almost 8 million genetic variants, the researchers found one with a significant association with a score that measures disability in people with multiple sclerosis, adjusted for age. On average, people with the marker required walking assistance 3.7 years earlier than those without it.
The team then examined brain tissue samples collected from a separate group of 290 people with multiple sclerosis who had died. On average, those with the marker had nearly twice the number of lesions in the outer layer of their brain and in their brainstem than those without it. The researchers say this indicates the variant has a connection to the neurological injuries that trigger the progression of multiple sclerosis.Get the most essential health and fitness news in your inbox every Saturday.
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