Experimental Research on the World’s Longest-Living Vertebrate Reveals New Anti-Aging Secrets

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Experimental Research on the World’s Longest-Living Vertebrate Reveals New Anti-Aging Secrets
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Science, Space and Technology News 2024

Recent studies on the Greenland shark, the longest-living vertebrate, reveal that its stable muscle metabolic activity across different ages may be key to its extraordinary longevity. Led by Mr. Ewan Camplisson from the University of Manchester, the research not only challenges previous beliefs that attribute the shark’s lifespan to its cold environment and minimal movement but also opens potential avenues for conservation strategies and human cardiovascular research.

Recent experimental research indicates that muscle metabolic activity might play a crucial role in the exceptional longevity of the world’s oldest living vertebrate, the Greenland shark. These insights could be valuable for conserving this vulnerable species amidst climate change and may also have implications for human cardiovascular health.with an expected lifespan of at least 270 years and a possible lifespan beyond 500 years.

To measure the metabolism of the sharks, Mr Camplisson and his team conducted enzyme assays on preserved muscle tissue samples from Greenland sharks. They measured the metabolic activity of these enzymes with a spectrophotometer across a range of different shark ages and environmental temperatures. In a world with a rapidly changing climate, long-lived species that are less able to adapt may be the most at risk of extinction. “A female Greenland shark may not become sexually mature until it is 150 years old and with such a long generation time, the species will have far less of a chance to adapt to anthropogenic changes in their environment,” says Mr Camplisson.

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