New data add to the body of evidence favoring the aromatase inhibitor therapy plus ovarian suppression over tamoxifen for premenopausal women with early invasive lobular carcinoma.
trials showed that women with premenopausal invasive lobular carcinoma , than those with invasive ductal carcinoma, experience a greater magnitude of benefit when treated with the aromatase inhibitor exemestane plus ovarian suppression vs tamoxifen plus ovarian suppression and tamoxifen alone.
Bottomline: On average, exemestane plus ovarian suppression is better than tamoxifen plus ovarian suppression, which is better than tamoxifen alone, he said. But the"absolute treatment benefits are directly correlated to individual patient risks."annual congress, reminded attendees that"as with many clinical questions, level I evidence from a phase 3 study will not be available, and therefore, clinical judgment remains critical in the selection of adjuvant therapy.
Exemestane plus ovarian suppression showed a larger disease-free survival benefit over tamoxifen in women with invasive lobular carcinoma than in those with invasive ductal carcinoma at a median follow-up of 12 years.
Malignant Breast Neoplasm Breast Carcinoma Lobular Cancer Lobular Carcinoma Cancer Malignant Neoplasia Carcinoma Malignant Neoplasm Ovarian Ablation Ovarian Suppression Aromatase Inhibitor Exemestane Tamoxifen Selective Estrogen Receptor Modulators SERM - Selective Estrogen Receptor Modulator Tumor Breast Mammary Gland Genomics Genomic Medicine
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Duke Coach on Packers OL Jacob Monk: ‘Truly A-Plus-Plus’“He’s an O-lineman in heart, mind, body and soul. Everything about him screams O-lineman,” Jacob Monk’s coach at Duke, Adam Cushing, told Packer Central.
Read more »
Peterborough teenager gets all clear from ovarian cancerA mother describes her relief after her daughter is given the all clear from ovarian cancer.
Read more »
Study links talc to ovarian cancer, with implications for J&J lawsuitsAria Bendix is the breaking health reporter for NBC News Digital.
Read more »
TikToker Taylor Odlozil Shares Haley's Last Words Before Dying From Ovarian CancerAmy Eley is the assistant managing editor and oversees the West Cost digital team for TODAY.com, covering breaking news, what's happening in pop culture, those viral TikTok videos and everything in between. She's currently based in Colorado.
Read more »
Mother rings 'Cancer Bell' to celebrate victory over ovarian cancerAutumn Gray gathered with family, friends, and medical team at Kaiser Permanente Oncology Unit.
Read more »
J&J subsidiary proposes paying about $6.48B over 25 years to settle talc ovarian cancer lawsuitsThe lawsuits filed against J&J had alleged its talcum powder caused users to develop ovarian cancer, through use for feminine hygiene, or mesothelioma, a cancer that strikes the lungs and other organs.
Read more »