A susceptibility to gain weight may be written into molecular processes of human cells, a new study indicates. The proof-of-concept study with a set of 22 twins found an epigenetic signature in buccal or cheek cells appearing only for the twins who were obese compared to their thinner siblings.
With more research, the findings could lead to a simple cheek swab test for an obesity biomarker and enable earlier prevention methods for a condition that effects 50% of U.S. adults, the researchers said.A susceptibility to gain weight may be written into molecular processes of human cells, a Washington State University study indicates.
The signature's systemic nature also suggests that something may have occurred early in one twin's life that triggered obesity susceptibility, Skinner added. It's also possible that it was inherited by one twin and not the other. The goal would be able to identify people earlier in life before they become obese so health care providers might help create interventions such as lifestyle changes, medication or both, said Duncan.
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