A group of novel synthetic opioids may be more potent than fentanyl and may even require more doses of the medication naloxone to reverse an overdose, a new study suggests.
A group of novel synthetic opioids emerging in illicit drugs in the United States may be more powerful than fentanyl, 1,000 times more potent than morphine, and may even require more doses of the medication naloxone to reverse an overdose, a new study suggests. Nitazenes are a synthetic opioid, like fentanyl, although the two drugs are not structurally related.
“Given the alarmingly high cardiac arrest rate for nitazene overdose, this study should energize harm-reduction policies. And given the emergence of dangerous toxic drugs in the illicit opioid supply in the United States, future research should examine clinical outcomes from new potent opioids as the supply continues to evolve,” Dr. Alex Manini, an author of the study and professor of emergency medicine at the Icahn School of Medicine at Mount Sinai, said in a news release.
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