Early life antibiotic increases risk of asthma: providing clues to a potential prevention adult asthma

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Early life antibiotic increases risk of asthma: providing clues to a potential prevention adult asthma
AllergyChronic IllnessHealthy Aging
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Early exposure to antibiotics can trigger long term susceptibility to asthma, according to new research.

Early life antibiotic increases risk of asthma: providing clues to a potential prevention adult asthma Importantly the research team isolated a molecule produced by gut bacteria that in the future could potentially be trialed as a simple treatment, in the form of a dietary supplement, for children at risk of asthma to prevent them developing the disease.

The first years of life are important in developing a stable gut microbiota, according to Professor Marsland."It is shaped first by food intake -- both milk and solid foods -- as well as genetics, and environmental exposures. Infants at high risk of allergies and asthma have been shown to have a disrupted and delayed maturation of the gut microbiome," he said.

This susceptibility was maintained long-term, even after the gut microbiome and IPA levels returned to normal, highlighting that this molecule's function was particularly important early in life.

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