Patients with persistent upper-back itch from notalgia paresthetica may get some relief with oral difelikefalin. DermTwitter familymedicine
as well. I'm able to control" almost all of my notalgia paresthetica patients, he added.
In his view, for this type of drug, he said,"the right home for it is more for a generalized neuropathic pruritis or nociplastic itch, vs something very localized which is more amenable to topical therapies.","would limit therapeutic use to only the most severe cases in my mind."Kim and co-author Mark Lebwohl, MD, are paid consultants/advisers to Cara Therapeutics. Other co-authors also reported ties to Cara.
Kwatra previously had done consulting work for Cara Therapeutics and is an advisory board member/consultant for AbbVie, Amgen, Arcutis Biotherapeutics, Aslan Pharmaceuticals, Castle Biosciences, Celldex Therapeutics, Galderma, Genzada Pharmaceuticals, Incyte Corporation, Johnson & Johnson, Leo Pharma, Novartis Pharmaceuticals Corporation, Pfizer, Regeneron Pharmaceuticals, and Sanofi and has served as an investigator for Galderma, Incyte, Pfizer, and Sanofi.
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