Childhood Obesity Doubles MS Odds in Young Adulthood

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Childhood Obesity Doubles MS Odds in Young Adulthood
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Children who are obese face double the odds of developing multiple sclerosis later in life, a new study warns. The overall odds for any one child to develop the neurodegenerative illness remains very low. However, the Swedish researchers believe the link could help explain...

Children who are obese face double the odds of developing multiple sclerosis later in life, a new study warns.

"There are several studies showing that MS has increased over several decades and obesity is believed to be one major driver for this increase," wrote a team led by Claude Marcus, of the Karolinska Institute in Stockholm. "Thanks to our prospective study design, we can confirm this theory."For the study, Marcus and his colleagues tracked data from 1995 through 2020, compiled by the Swedish Childhood Obesity Treatment Register.

The result: While 0.06% of the non-obese children went on to develop MS, the rate more than doubled, to 0.13%, among people who had been obese during childhood. MS was diagnosed at roughly the same average age — about 23 — regardless of people's weight history, the team added."Paediatric obesity is associated with several autoimmune diseases and the leading hypothesis is that the persistent low-grade inflammatory state, typically observed in obesity, is mediating the association," Marcus' group theorized.

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