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The half-hour series hails from Chuck Lorre and Marco Pennette, inspired by Pennette's experience as a transplant recipient. It kicks off when Drew , a therapist and newly divorced dad, is faced with finding a kidney donor when he runs into Gina , a rough-around-the-edges woman from his past who volunteers her own. Together, they form an unlikely and life-affirming friendship, as they begin a journey that will forever affect both of their lives.
will also kick off its 18th season on Tuesday, Nov. 17, with the milestone 400th episode airing the week after. Beginning Sunday, Nov. 8, it's an all-
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